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1) Is it that much more effort to set up a left/right page template? In FrameMaker, the extra effort is minimal and once it is set up you don't have to worry about it.
2) Does a left/right layout detract from the usability of your PDF? Probably not.
Make that three questions:
3) If you want to avoid "bookthink", why are you using PDF as an output format? Because of its page presentation, PDFs are notoriously bad on tablets and phones.
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