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Peggy asked about headings in 'downstyle.'
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I only use the 'up- and down-style' for the title of the manual.
All other headings are downstyle. They look clean and easy to read. Mixed case
(up- and down-) seems to add clutter to the page.
You can emphasize the headings with bolding and a larger size; even just using a
san serif font helps it stand apart from the text (assuming you use serif for
the text).